3D hyperpolarized C-13 EPI with calibrationless parallel imaging
نویسندگان
چکیده
منابع مشابه
3D hyperpolarized C-13 EPI with calibrationless parallel imaging.
With the translation of metabolic MRI with hyperpolarized 13C agents into the clinic, imaging approaches will require large volumetric FOVs to support clinical applications. Parallel imaging techniques will be crucial to increasing volumetric scan coverage while minimizing RF requirements and temporal resolution. Calibrationless parallel imaging approaches are well-suited for this application b...
متن کاملQuantified pH imaging with hyperpolarized (13) C-bicarbonate.
PURPOSE Because pH plays a crucial role in several diseases, it is desirable to measure pH in vivo noninvasively and in a spatially localized manner. Spatial maps of pH were quantified in vitro, with a focus on method-based errors, and applied in vivo. METHODS In vitro and in vivo (13) C mapping were performed for various flip angles for bicarbonate (BiC) and CO2 with spectral-spatial excitat...
متن کاملHyperpolarized C-13
Where tanh is the hyperbolic tangens function, h the Planck constant, BBo is the main magnetic field strength, kBB the Boltzmann constant and T is the temperature. At a magnetic field of 1.5 T the polarization of the protons (H) at body temperature is only ∼5 x 10 and for C ∼1.0 x 10. The polarization is proportional to the magnetic field strength. Consequently, a 3 T scanner will result in a d...
متن کاملRapid imaging of hyperpolarized gas using EPI.
Rapid repetitive MRI of hyperpolarized (HP) gases using echo-planar imaging (EPI) has been theoretically investigated and experimentally demonstrated for (3)He in human lung. A quantitative treatment of signal attenuation and magnetization consumption for the unique circumstance of a rapidly diffusing nonrenewable magnetization source has been performed. Rapid (compared to the human respiratory...
متن کاملImaging carbonic anhydrase activity using hyperpolarized 13 C - labeled bicarbonate
Introduction We have shown previously that C-labeled bicarbonate (HCO3 ) can be hyperpolarized using Dynamic Nuclear Polarisation (DNP) and that when this is injected in vivo, the enzyme carbonic anhydrase (CA) rapidly interconverts this with carbon dioxide (CO2) [1]. Furthermore, we have also shown that selective saturation of the CO2 signal in vivo will decrease the H CO3 signal in the presen...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Magnetic Resonance
سال: 2018
ISSN: 1090-7807
DOI: 10.1016/j.jmr.2018.02.011